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Santiago E Farias Selected Research

Pharmaceutical Preparations

1/2016Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design.
4/2015Effect of attachment site on stability of cleavable antibody drug conjugates.
2/2014Mass spectrometric characterization of transglutaminase based site-specific antibody-drug conjugates.

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Santiago E Farias Research Topics

Disease

3Neoplasms (Cancer)
01/2016 - 02/2014
3Brain Injuries (Brain Injury)
06/2014 - 06/2011
2Traumatic Brain Injuries (Traumatic Brain Injury)
06/2014 - 06/2011
1Cognitive Dysfunction
06/2014
1Brain Edema (Cerebral Edema)
06/2014
1Neurologic Manifestations (Neurological Manifestations)
06/2014
1Wounds and Injuries (Trauma)
06/2014
1Edema (Dropsy)
06/2011
1Reperfusion Injury
06/2011
1Neuroinflammatory Diseases
05/2010
1Ischemia
09/2008
1Decapitation
09/2008
1Brain Ischemia (Cerebral Ischemia)
09/2008

Drug/Important Bio-Agent (IBA)

3Pharmaceutical PreparationsIBA
01/2016 - 02/2014
3Immunoconjugates (Immunoconjugate)IBA
01/2016 - 02/2014
2LipidsIBA
06/2011 - 09/2008
2Arachidonic Acid (Vitamin F)IBA
05/2010 - 09/2008
1auristatinIBA
01/2016
1MK-886IBA
06/2014
1Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
06/2014
1Proteins (Proteins, Gene)FDA Link
06/2014
1LeukotrienesIBA
06/2014
15-Lipoxygenase-Activating Protein InhibitorsIBA
06/2014
1Monoclonal AntibodiesIBA
02/2014
1Biomarkers (Surrogate Marker)IBA
11/2011
112-Hydroxy-5,8,10,14-eicosatetraenoic AcidIBA
11/2011
1Adenosine Triphosphatases (ATPase)IBA
06/2011
1CeramidesIBA
06/2011
1PotassiumIBA
06/2011
1AlkaliesIBA
06/2011
1SodiumIBA
06/2011
1Phospholipids (Phosphatides)FDA LinkGeneric
06/2011
1Phosphorylcholine (Phosphocholine)IBA
06/2011
1LithiumIBA
05/2010
1LipopolysaccharidesIBA
05/2010
1IsoprostanesIBA
09/2008
1docosapentaenoic acidIBA
09/2008
1EicosanoidsIBA
09/2008
1Docosahexaenoic AcidsIBA
09/2008

Therapy/Procedure

1Intraventricular Infusions
05/2010